ENDOGENOUS HCN CHANNELS MODULATE THE FIRING ACTIVITY OF GLOBUS PALLIDUS NEURONS IN PARKINSONIAN ANIMALS

The globus pallidus occupies a critical position in the indirect pathway of the basal ganglia motor control system.Hyperpolarization-activated cyclic-nucleotide gated (HCN) channels play an important role in the modulation of neuronal excitability.In vivo extracellular single unit recording, behavioral test and immunohistochemistry were performed t

Crack propagation produced by frost heave affects the durability of slab-track structures in high-humidity and cold regions in China.This work is intended to reveal the evolution laws of frost-heave crack propagation, establish evaluation criteria for crack propagation, and investigate factors involved in frost-heave crack propagation.Firstly, by p